Clinical Trials

Click on the icons below for trial documentation, data entry and other useful links.

Upcoming and recruiting Trials

EMPRESS

The Empirical Meropenem vs Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an upcoming investigator-initiated, international, parallel-group, randomised, open-label, adaptive clinical trial with an integrated feasibility phase.

The EMPRESS will use the logistic framework and methods developed as part of the Intensive Care Platform Trial (INCEPT) programme.

GODIF

Goal directed fluid removal with furosemide in intensive care patients with fluid overload. Click on the icon to access screening, data entry and trial documents.
Eligibility.


Non-Recruiting Trials

HOT-COVID

An amendment to the HOT-ICU trial, exploring benefits and harms of two oxygenation targets for ICU patients with COVID-19 and acute hypoxic respiratory failure. Click on the icon to access screening, data entry and trial documents.

Recruitment completed


Completed Trials

AID-ICU

Agents Intervening against Delirium for patients in the Intensive Care Unit. Click on the icon to access screening, data entry and trial documents. Recruitment completed

CLASSIC

Conservative versus Liberal Approach to fluid therapy of Septic Shock in Intensive Care. Click on the icon to access screening, data entry and trial documents.
Recruitment completed

HOT-ICU

Handling Oxygenation Targets (HOT-ICU) tests oxygen levels for ICU patients with acute hypoxic respiratory failure.Click on the icon to access trial documents.

COVID STEROID

Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia – the COVID STEROID trial. Click on the icon to access trial documents.

COVID STEROID 2

Higher vs. Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia: the COVID STEROID 2 trial. Click on the icon to access screening, data entry and trial documents.

SUP-ICU

Compared the effects of stress ulcer prophylaxis with an acid suppressant (pantoprazole) versus placebo. Click on the icon to access trial documents